Vaccines and Immunotherapy — Prelims Strategy

Prelims Strategy

For Prelims, a strong foundation in the basic science of vaccines and immunotherapy is essential. Focus on understanding the core mechanism of each vaccine type (live attenuated, inactivated, subunit, mRNA, viral vector) and immunotherapy approach (mAbs, checkpoint inhibitors, CAR-T).

Memorize key examples for each, especially those relevant to India (Covaxin, Covishield, Sputnik V, indigenous mRNA initiatives). Pay close attention to specific terms like 'cold chain,' 'adjuvant,' 'herd immunity,' 'AEFI,' 'cytokine release syndrome,' and 'efficacy vs.

effectiveness.' Create flashcards for quick recall of facts, figures, and specific vaccine names. Understand the regulatory bodies like CDSCO and their functions. Practice MCQs that test conceptual clarity and factual accuracy, including those that require distinguishing between similar terms or mechanisms.

Vyyuha's Quick Recall mnemonics will be particularly useful here. Emphasize recent developments and current affairs related to new approvals, policy changes, and India's contributions, as these are frequently tested.